Pipeline Overview

We are focused on the development and commercialization of innovative therapeutics for the treatment of cancer.

PreclinicalClinicalMarketed
 IndicationProof of PrincipleSafetyDose OptimizationClinical ActivityPivotalCommercial
Heme Malignancies
Emavusertib*
IRAK4
 IRAK4-driven Leukemia
(AML/MDS)

TakeAim Leukemia

Emavusertib*
IRAK4
 IRAK4-driven Lymphoma
(NHL, CLL, WM)

TakeAim Lymphoma

Fimepinostat
HDAC/PI3K
 MYC-altered Cancers

Immune Checkpoint Inhibitors
CA-327*
TIM3/PDL1
 PDL1/TIM3-expressing Cancers

CA-170**
VISTA/PDL1
 PDL1/VISTA-expressing Cancers

Approved Drug
Erivedge***
Hedgehog
 Basal Cell Carcinoma

DrugIndicationStage
Heme Malignancies
Emavusertib*
IRAK4
 IRAK4-driven Leukemia
(AML/MDS)		Clinical Activity
Emavusertib*
IRAK4
 IRAK4-driven Lymphoma
(NHL, CLL, WM)		Clinical Activity
Fimepinostat
HDAC/PI3K
 MYC-altered CancersClinical Activity
Immune Checkpoint Inhibitors
CA-327*
TIM3/PDL1
 PDL1/TIM3-expressing CancersProof of Principle
CA-170**
VISTA/PDL1
 PDL1/VISTA-expressing CancersClinical Activity
Approved Drug
Erivedge***
Hedgehog
 Basal Cell CarcinomaCommercial

* IP licensed from Aurigene
** IP licensed to Aurigene
*** IP licensed to Genentech

Indicates a program included in the Curis intellectual property portfolio, but not currently designated as a priority for clinical development.


Moffitt Cancer Center
1320)
1322)

MAtch:1322 / 1322 /1950-Moffitt Cancer Center


This Location ALREADY exists:Moffitt Cancer Center
Winship Cancer Institute
1320)
1322)

MAtch:1322 / 1322 /1950-Winship Cancer Institute


This Location ALREADY exists:Winship Cancer Institute
Northwestern Memorial Hospital
1320)
1322)

MAtch:1322 / 1322 /1950-Northwestern Memorial Hospital


This Location ALREADY exists:Northwestern Memorial Hospital
University of Chicago Medical Center
1320)
1322)

MAtch:1322 / 1322 /1950-University of Chicago Medical Center


This Location ALREADY exists:University of Chicago Medical Center
Dana Farber Cancer Institute
1320)
1322)

MAtch:1322 / 1322 /1950-Dana Farber Cancer Institute


This Location ALREADY exists:Dana Farber Cancer Institute
Oncology Hematology West, PC dba Nebraska Cancer Specialists
1320)
1322)

MAtch:1322 / 1322 /1950-Oncology Hematology West, PC dba Nebraska Cancer Specialists


This Location ALREADY exists:Oncology Hematology West, PC dba Nebraska Cancer Specialists
Albert Einstein Medical College
1320)
1322)

MAtch:1322 / 1322 /1950-Albert Einstein Medical College


This Location ALREADY exists:Albert Einstein Medical College
University of Rochester Medical Center
1320)
1322)

MAtch:1322 / 1322 /1950-University of Rochester Medical Center


This Location ALREADY exists:University of Rochester Medical Center
Novant Health Hematology - Forsyth
1320)
1322)

MAtch:1322 / 1322 /1950-Novant Health Hematology - Forsyth


This Location ALREADY exists:Novant Health Hematology – Forsyth
The Ohio State University Wexner Medical Center - James Cancer Hospital
1320)
1322)

MAtch:1322 / 1322 /1950-The Ohio State University Wexner Medical Center - James Cancer Hospital


This Location ALREADY exists:The Ohio State University Wexner Medical Center – James Cancer Hospital
The University of Texas MD Anderson Cancer Center
1320)
1322)

MAtch:1322 / 1322 /1950-The University of Texas MD Anderson Cancer Center


This Location ALREADY exists:The University of Texas MD Anderson Cancer Center
Vseobecna Fakultni nemocnice v Praze
1320)
1322)

MAtch:1322 / 1322 /1950-Vseobecna Fakultni nemocnice v Praze


This Location ALREADY exists:Vseobecna Fakultni nemocnice v Praze
Service d'hématologie clinique CHU de Nice
1320)
1322)

MAtch:1322 / 1322 /1950-Service d'hématologie clinique CHU de Nice


This Location ALREADY exists:Service d’hématologie clinique CHU de Nice
APHP - Sorbonne Universite
1320)
1322)

MAtch:1322 / 1322 /1950-APHP - Sorbonne Universite


This Location ALREADY exists:APHP – Sorbonne Universite
APHP - Hopital Saint Louis
1320)
1322)

MAtch:1322 / 1322 /1950-APHP - Hopital Saint Louis


This Location ALREADY exists:APHP – Hopital Saint Louis
Marien Hospital Dusseldorf; Klinik fur Onkologie und Hamatologie, Palliativmedizin
1320)
1322)

MAtch:1322 / 1322 /1950-Marien Hospital Dusseldorf; Klinik fur Onkologie und Hamatologie, Palliativmedizin


This Location ALREADY exists:Marien Hospital Dusseldorf; Klinik fur Onkologie und Hamatologie, Palliativmedizin
Universitatsklinikum Leipzig; Medizinische Klinik und Poliklinik I
1320)
1322)

MAtch:1322 / 1322 /1950-Universitatsklinikum Leipzig; Medizinische Klinik und Poliklinik I


This Location ALREADY exists:Universitatsklinikum Leipzig; Medizinische Klinik und Poliklinik I
Klinikum rechts der Isar der Technischen Universitat Munchen
1320)
1322)

MAtch:1322 / 1322 /1950-Klinikum rechts der Isar der Technischen Universitat Munchen


This Location ALREADY exists:Klinikum rechts der Isar der Technischen Universitat Munchen
Universitatsklinikum Munster
1320)
1322)

MAtch:1322 / 1322 /1950-Universitatsklinikum Munster


This Location ALREADY exists:Universitatsklinikum Munster
Soroka University MC
1320)
1322)

MAtch:1322 / 1322 /1950-Soroka University MC


This Location ALREADY exists:Soroka University MC
Edith Wolfson Medical Center
1320)
1322)

MAtch:1322 / 1322 /1950-Edith Wolfson Medical Center


This Location ALREADY exists:Edith Wolfson Medical Center
Hadassah University MC
1320)
1322)

MAtch:1322 / 1322 /1950-Hadassah University MC


This Location ALREADY exists:Hadassah University MC
Azienda Ospedaliera Santa Croce e Carle
1320)
1322)

MAtch:1322 / 1322 /1950-Azienda Ospedaliera Santa Croce e Carle


This Location ALREADY exists:Azienda Ospedaliera Santa Croce e Carle
Instituto Romagnolo per lo Studio dei Tumori "Dino Amadori"
1320)
1322)

MAtch:1322 / 1322 /1950-Instituto Romagnolo per lo Studio dei Tumori "Dino Amadori"


This Location ALREADY exists:Instituto Romagnolo per lo Studio dei Tumori "Dino Amadori"
Uniwersyteckie Centrum Kliniczne Osrodek Badan Klinicznych Wczesnych Faz
1320)
1322)

MAtch:1322 / 1322 /1950-Uniwersyteckie Centrum Kliniczne Osrodek Badan Klinicznych Wczesnych Faz


This Location ALREADY exists:Uniwersyteckie Centrum Kliniczne Osrodek Badan Klinicznych Wczesnych Faz
University Hospital in Krakow
1320)
1322)

MAtch:1322 / 1322 /1950-University Hospital in Krakow


This Location ALREADY exists:University Hospital in Krakow
Hospital de la Santa Creu I Sant Pau (Neuvo Hospital)
1320)
1322)

MAtch:1322 / 1322 /1950-Hospital de la Santa Creu I Sant Pau (Neuvo Hospital)


This Location ALREADY exists:Hospital de la Santa Creu I Sant Pau (Neuvo Hospital)
Hospital Universitaro del a Princesa
1320)
1322)

MAtch:1322 / 1322 /1950-Hospital Universitaro del a Princesa


This Location ALREADY exists:Hospital Universitaro del a Princesa
MD Anderson Cancer Center Madrid
1320)
1322)

MAtch:1322 / 1322 /1950-MD Anderson Cancer Center Madrid


This Location ALREADY exists:MD Anderson Cancer Center Madrid
Hospital Universitario Virgen del Rocio
1320)
1322)

MAtch:1322 / 1322 /1950-Hospital Universitario Virgen del Rocio


This Location ALREADY exists:Hospital Universitario Virgen del Rocio1